Gene candidates for miRNA regulation.
These genes showed a large differential (≥5, ≤ −5) in miRNAs predicted to target their mRNA and that are up- or downregulated in adult populations vs. young. This differential was calculated by subtracting the number of downregulated miRNA from the upregulated miRNA. A positive number would predict downregulated protein in adults, whereas a negative number would predict upregulated protein.
| Gene | miRNA Differential | Gene | miRNA Differential |
|---|---|---|---|
| CYP2B6 | −7 | CYP3A4 | 5 |
| CYP2S1 | −5 | CYP3A5 | 8 |
| CYP2U1 | −5 | CYP51A1 | 5 |
| CYP4F12 | −5 | GSTM4 | 10 |
| CYP4F22 | −6 | GSTO1 | 6 |
| FMO3 | −5 | SULT2A1 | 5 |
| GSTA2 | −5 | ||
| GSTM5 | −5 | ||
| GSTO2 | −9 | ||
| GSTT2 | −5 | ||
| mGST1 | −6 | ||
| UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A7 | −5 | ||
| UGT1A5, UGT1A8, UGT1A9, UGT1A10 | −6 |