Pharmacokinetic parameters of carbazeran in humanized-liver mice and control mice after single oral administration of carbazeran at 10 mg/kg
↵a Ratios of pharmacokinetic parameters in humanized-liver mice to those in control mice.
↵b The AUC0-last and AUC0-inf values represent the mean ± S.D., n = 4 animals.
↵** P < 0.01 vs. the control mice.