TABLE 3

Summary of IC₅₀ values of abacavir, entecavir, and zidovudine for inhibition of [³H]uridine uptake

A single component IC₅₀ equation was used to generate values for total uptake and ENT2-mediated uptake (+100 nM NBMPR), and the ENT1 component was generated by subtracting the ENT2-mediated component from total uptake. An unpaired t test was used to determine statistical significance. All values are reported as mean ± S.D. of six replicate values (n = 3).