TABLE 1

Standardized tissue composition values are from Ruark et al. (2014), unless indicated otherwise.

TissueEmbedded ImageEmbedded ImageEmbedded Imagefpl (Poulin et al., 2001)Embedded ImageEmbedded ImageEmbedded ImagepH (Schmitt, 2008)few (Rodgers et al., 2005)fiw (Rodgers et al., 2005)AR (Rodgers et al., 2005)LR (Rodgers et al., 2005)
Bone0.446 (Rodgers et al., 2005)0.268 (Open Systems Pharmacology)0.268 (Open Systems Pharmacology)0.00110.074 (Poulin et al., 2001)0.0016 (Rodgers and Rowland, 2006)8E−04 (Open Systems Pharmacology)70.10.3460.10.05
Brain0.782 (Rodgers et al., 2005)0.1070.080.05650.0450.05530.020227.10.1620.6200.0480.041
Adipose0.152 (Rodgers et al., 2005)0.8000.050.0020.7980.04780.00677.10.1350.0170.0490.069
Heart0.776 (Rodgers et al., 2005)0.10.170.01660.0890.00790.003097.10.320.4560.1570.16
Kidney0.756 (Rodgers et al., 2005)0.0520.170.01620.0360.01660.003877.220.2730.4830.130.137
Gut0.757 (Rodgers et al., 2005)0.062 (Open Systems Pharmacology)0.133 (Open Systems Pharmacology)0.01630.0487 (Poulin et al., 2001)0.0124 (Rodgers and Rowland, 2006)3.5E−03 (Open Systems Pharmacology)7.40.2820.4750.1580.141
Liver0.734 (Rodgers et al., 2005)0.0670.180.02520.0370.01150.002587.230.1610.5730.0860.161
Lung0.782 (Rodgers et al., 2005)0.010.180.0090.0030.00560.00146.60.3360.4460.2120.168
Muscle0.748 (Rodgers et al., 2005)0.0190.170.00720.0130.00920.00196.810.1180.630.0640.059
Skin0.673 (Rodgers et al., 2005)0.10.290.01110.0360.05020.013827.00.3820.2910.2770.096
Spleen0.786 (Rodgers et al., 2005)0.0280.190.01980.0140.01030.001917.00.2070.5790.0970.207
Plasma0.9280.0090.070.002250.0030.00509.7E−047.30.0296E−04
RBCs0.6630.0050.330.0020.00255E−057.20.663
  • Embedded Image, fractional volume of acidic phospholipids; Embedded Image, fractional volume of extracellular water; Embedded Image, fractional volume of intracellular water; Embedded Image, fractional volume of lipid; Embedded Image, fractional volume of neutral lipids; Embedded Image, fractional volume of neutral phospholipids; Embedded Image, fractional volume of phospholipids; Embedded Image, fractional volume of protein; Embedded Image, fractional volume of water; RBC, red blood cell.