5-Hydroxypimozide | 6-Hydroxypimozide | DHPBI | Sum of Metabolites^{a} | Pimozide Depleted^{b} | |
---|---|---|---|---|---|

Amount (pmol) | 0.27 (0.040) | 0.11 (0.035) | 2.4 (0.20) | 2.8 (0.17) | 3.1 (0.80) |

% Depleted Accounted^{c} | 8.7 (1.3) | 3.5 (1.1) | 78 (6.5) | 90 (5.5) | N/A |

N/A, not applicable.

↵

^{a}Denotes sum of amounts of DHPBI, 5-hydroxypimozide, and 6-hydroxypimozide formed during each incubation.↵

^{b}Denotes the difference between pimozide amounts measured at time 0 and 20 min in each incubation.↵

^{c}Sum of metabolite amounts divided by amount of pimozide depleted over the course of the incubation, expressed as a percentage (see eq. 1).