TABLE 3

Summary of GSH and GSSG levels, millimoles per kilogram, in whole livers of acetate- (control) and DCA-treated rats

Age, sex of ratGSH (mM)GSSG (mM)GSH:GSSG
ControlDCAControlDCAControlDCA
Young femalea4.67 ± 0.415.63 ± 1.620.14 ± 0.050.17 ± 0.0936.00 ± 8.3039.72 ± 14.5
Young malea4.19; 6.62b6.39 ± 1.030.17; 0.17b0.19 ± 0.0625.21; 39.17b34.78 ± 5.07
Adult femalec5.59 ± 0.48d7.05 ± 0.39d0.21 ± 0.060.28 ± 0.0827.82 ± 7.7627.13 ± 9.41
  • a Mean ± S.D. (n = 4).

  • b Individual values reported from two determinations.

  • c Mean ± S.D. (n = 8).

  • d P < 0.0001 control vs. DCA-treated (two-tailed Student’s t test).