TABLE 1

The ratio of 12α-OH BAs to non–12α-OH BAs in livers and serum of two genders

12α-OH BAs: CA, DCA, TCA, TDCA; non–12α-OH BAs: CDCA, LCA, UDCA, HDCA, MDCA, TCDCA, TLCA, TUDCA, TMDCA, THDCA, MCAs and TMCAs.

Diet	Male		Female
Diet	Liver	Serum	Liver	Serum
AIN-93M purified	0.24 ± 0.05	0.53 ± 0.15	0.57 ± 0.05	1.55 ± 0.2
Laboratory chow	0.61 ± 0.1	0.69 ± 0.15	0.8 ± 0.1	1.28 ± 0.25
Diet-restriction	2.12 ± 0.55^*	2.14 ± 0.6^*	1.65 ± 0.15^*	2.02 ± 0.35
High fructose	0.47 ± 0.45	0.33 ± 0.15	0.8 ± 0.05	1.5 ± 0.15
High fat	0.29 ± 0.05	0.5 ± 0.20	0.8 ± 0.25	1.51 ± 0.35
Atherogenic	30.09 ± 3.25^*	48.47 ± 9.8^*	21.73 ± 8.75^*	41.24 ± 16.35^*
Western	0.26 ± 0.1	0.61 ± 0.2	0.3 ± 0.05	0.82 ± 0.2
Low n-3 FA	0.23 ± 0.05	0.56 ± 0.25	0.51 ± 0.2	1.53 ± 0.35
EFA deficient	0.28 ± 0.1	0.22 ± 0.1	0.56 ± 0.15	1.05 ± 0.3

↵^* Indicates P < 0.05 when compared with the AIN-93M purified diet. Mean values ± S.D. are shown.