TABLE 1

Pharmacokinetic parameters of cannabidiol in the maternal plasma and fetus

The results of the analysis are displayed as means ± S.D.

AUC0–12AUCinfMRT0–12MRTinft1/2αt1/2βCLtotVdαVdβ
Maternal: ng*h/ml
Fetal: ng*h/g
hl/h per kilograml/kg
Maternal sample (plasma) (n = 5)1295.2 ± 166.01692.1 ± 417.51.1 ± 0.071.7 ± 0.30.7 ± 0.14.9 ± 1.27.7 ± 1.02.2 ± 0.155.1 ± 2.4
Fetal sample (whole body) (n = 15)866.4 ± 214.2874.5 ± 210.01.7 ± 0.21.8 ± 0.40.8 ± 0.22.3 ± 0.5aaa
  • a Can't calculate.