Calculation of REF values used for OATP1B1 and OATP1B3
| HEK293 overexpressing cells | Hepatocytes | HEK293 overexpressing cells | Hepatocytes | REF | |
|---|---|---|---|---|---|
| pmol/mg protein | pmol per 106 cells | mg protein per 106 cells | mg protein per 106 cells | ||
| OATP1B1 | 1.51 | 6.91 | 0.239 | 0.294 | 5.63 |
| OATP1B3 | 0.672 | 1.02 | 0.238 | 0.294 | 1.87 |