TABLE 5

Comparison of plasma AUCR between the NMP porcine liver model and in vivo studies

In all three clinical studies, the statins were dosed as a cocktail in healthy volunteers.

NMP Porcine Liver Model (Current Study)Mori et al., 2019Takehara et al., 2018Prueksaritanont et al., 2017
Atorvastatin7.247.296.110.01
Pitavastatin2.634.012.84.45
Rosuvastatin3.102.482.45.38