Categorization of clearance data

Observed t1/2CategorySubstrate Class
t1/2 ≤ 30 minUnstable1
t1/2 > 30 minStable0
Low signalaBLQBlank
Unable to reasonably fit line to databINC
Analyte not detected in mass spectrometerN/F
  • a y-intercept of line fitting the Ln(analyte/IS) versus time plot is ≤ −9.0.

  • b Albendazole also assigned as INC due to its use as IS.