TABLE 1

Correlation of small intestinal protein abundances of DTs and DMEs with age in pediatric patients

Statistics with All ValuesStatistics without Imputed Values
Villin CorrectedWithout Correction for VillinVillin CorrectedWithout Correction for Villin
JejunumIleumJejunumIleumJejunumIleumJejunumIleum
ρaP valueρP valueρP valueρP valueρP valueρP valueρP valueρP value
BCRP0.6444b*0.13670.35420.4316nsc0.11290.44490.6444*0.15160.34390.4316ns0.20570.197
MRP2−0.3161ns−0.05850.693−0.0730ns−0.13590.3569−0.3161ns−0.16880.2622−0.0730ns−0.25250.0904
MCT1−0.4255ns−0.38970.0062−0.0912ns−0.50630.0002−0.3096ns−0.13750.40380.1506ns−0.32090.0464
MRP3−0.4377ns0.2040.1643−0.304ns0.18810.2004−0.4377ns0.17920.2624−0.304ns0.21330.1806
ASBT0.1398ns0.2870.0480.3665ns0.31770.0278−1,0000ns−0.34730.18751,0000ns0.21510.2913
OATP2B1−0.2067ns−0.07890.5938−0.1459ns−0.14730.3179−0.2067ns−0.07890.5938−0.1459ns−0.14730.3179
MDR10.304ns0.32030.02640.1763ns0.21330.14540.304ns0.32030.02640.1763ns0.21330.1454
PEPT10.07903ns0.38120.00750.2979ns0.17470.23510.07903ns0.38120.00750.2979ns0.17470.2351
OCT1−0.2553ns−0.17190.2426−0.4677ns−0.2080.1561−0.1622ns−0.26140.24−0.8469*−0.34370.1001
UGT1A10.4377ns0.43410.00210.4062ns0.31620.02860.6307ns0.37130.02370.6667ns0.22990.171
UGT1A10−0.2492ns0.11420.4395−0.0598ns0.20150.16960.5ns0.31290.15620.5ns0.7124<0.0001
CYP2C19−0.0486ns−0.29180.0442−0.0910ns−0.41880.0031−0.7714ns−0.28250.1915−0.8214*−0.24410.2617
UGT2B7−0.2492ns−0.37490.00860.04878ns−0.25220.0838−0.2492ns−0.44880.0020.04878ns-0.30750.0399
CYP3A40.304ns0.01710.90810.3465ns−0.09030.54150.304ns0.14140.36010.3465ns0.02470.8737
CYP3A50.2067ns0.18990.19620.2805ns0.07490.6129−0.0838ns0.099960.5561−0.0120ns−0.07860.639
VIL10.3769ns0.00690.96290.3769ns0.00690.9629
  • aρ: Spearman correlation coefficient.

  • bP values significant at P < 0.05 without FDR correction are bolded; values significant after FDR correction are shaded (FDR < 0.05).

  • cns, not significant.