The availability of DT-related data types and groups among those ten databases (shown in Fig. 1) that provided the information of drugs and their corresponding transporters (DTs)
‘√’ indicated that the data type is available, whereas ‘–’ denotes that the data type is not available.
| ChEMBL | DrugBank | TTD | IUPHAR BPS | PharmGKB | KEGG | UCSF-FDA TransPortal | Trans former | Metrabase | VARIDT | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Expression, Distribution, and Function Data of DTs | Disease-Varied Expression | – | – | – | – | – | – | – | – | – | √ |
| Organism-Specific Abundance | – | – | – | – | – | – | – | – | – | √ | |
| Protein Functional Family | – | – | – | – | √ | – | – | – | – | √ | |
| Protein Sequence Information | – | – | – | – | – | – | – | – | – | √ | |
| Tissue-Differential Distribution | – | – | √ | – | √ | – | √ | – | √ | √ | |
| Polymorphism Data of DTs | Cytogenetic Location Information | – | – | – | – | √ | – | – | – | – | √ |
| Genetically Correlated Phenotype | – | – | – | – | √ | – | – | – | – | √ | |
| Genetic Variant and Frequency | – | – | – | – | √ | – | – | – | – | √ | |
| Genetically Induced Disease | – | – | – | – | √ | – | – | – | – | √ | |
| Structure-related Data of DTs | Species-Specific Evolution | – | – | – | – | – | – | – | √ | – | – |
| Whole Protein Structure | – | – | – | – | – | – | – | √ | – | – | |
| Epigenetic Data of DTs | DNA/histone Methylation Acetylation | – | – | – | – | – | – | – | – | – | √ |
| Noncoding RNA Regulation | – | – | – | – | – | – | – | – | – | √ | |
| Exogenous Substances of DTs | Clinical Drug-drug Interaction | – | – | – | – | – | – | √ | √ | – | √ |
| Exogenous Regulatory Substrates | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ | |
| Transporter Inhibitor and Inducer | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ |