Table 6

Expression levels of reductases in pooled HLC, HLM, and expression systems measured by LC-MS/MS

ProteinMRMExpression Level (pmol/mg)REFREF
m/zExpression SystemHLC (Average)HLM (Average)(Average)
AKR1C2566.0 / 930.522467(64)19(-)0.300.24
566.0 / 687.332760ND0.18
AKR1C3746.6 / 952.51118169(159)13(14)0.150.14
746.6 / 881.51229148150.12
AKR1C4740.6 / 940.527254(51)15(-)0.200.18
740.6 / 869.529849ND0.16
CBR1423.0 / 731.419322(22)ND(-)0.110.13
423.0 / 575.418423ND0.14
HSD11B1387.9 / 562.3269ND(-)76(73)0.280.29
387.9 / 463.3244ND700.29
  • ND, not detected.