TABLE 4

Percentage of the administered dose recovered following a 16 mg/100 µCi or 3.7 MBq oral dose of 14C-emvododstat on Day 7 in healthy male human subjects

DoseTime Interval (h)Mean ± S.D. Percentage of Dose Recovered
UrineFecesTotal
16 mg/100 µCi0–240a6.0 ± 2.119.9 ± 3.525.9 ± 5.1
0–∞b37.3 ± 2.9c56.6 ± 15.7d94.7 ± 15.6d
  • aN = 7.

  • bExtrapolated to infinity based on excretion rate constant.

  • cN = 4.

  • dN = 3.