Human adult hepatocytes in primary monolayer culture: Maintenance of mixed function oxidase and conjugation pathways of drug metabolism
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Mechanism of Impila (Callilepis laureola)-induced cytotoxicity in Hep G2 cells
2002, Clinical BiochemistryInduction of nuclear transcription factors, cytochrome P450 monooxygenases, and glutathione S-transferase alpha gene expression in Aroclor 1254-treated rat hepatocyte cultures
2001, Biochemical PharmacologyCitation Excerpt :Control samples contained water instead of cDNA, and it should be noted that oligonucleotide dimers were produced in some of the PCR cocktails, but could easily be distinguished by the melting point analysis. This assay was carried out essentially as described by Grant et al. [26]. Control cells and cells treated with Aroclor 1254 were incubated with 10 μM EROD and 10 μM dicumerol (Sigma), and the supernatants were removed from the cultures at time points 0, 1, 2, 3, and 4 hr.
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