review
The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein

https://doi.org/10.1016/0167-5699(94)90138-4Get rights and content

Abstract

Following an acute phase stimulus, such as infection or physical injury, many liver-derived plasma proteins are increased in concentration. These provide enhanced protection against invading micro-organisms, limit tissue damage and promote a rapid return to homeostasis. Diana Steel and Alexander Whitehead discuss the gene structure, regulation and possible clinical significance of the most dramatically induced acute phase reactants.

References (72)

  • H. Baumann et al.

    J. Biol. Chem.

    (1991)
  • H. Schooltink et al.

    FEBS Lett.

    (1992)
  • D. Thompson et al.

    Cytokine

    (1991)
  • B.R. Shiels et al.

    J. Biol. Chem.

    (1987)
  • M. Yiangou et al.

    Biochim. Biophys. Acta

    (1993)
  • M.B. Pepys et al.

    Adv. Immunol.

    (1983)
  • F.A. Robey et al.

    J. Biol. Chem.

    (1984)
  • M.B. Pepys et al.

    Biochem. Biophys. Res. Commun.

    (1987)
  • F. Breviario et al.

    J. Biol. Chem.

    (1992)
  • C.I. Bristow et al.

    Mol. Immunol.

    (1986)
  • N.D. Goldman et al.

    J. Biol. Chem.

    (1987)
  • M.K. Ganapathi et al.

    Biochem. Biophys. Res. Commun.

    (1988)
  • V. Poli et al.

    Cell

    (1990)
  • S.P. Li et al.

    J. Biol. Chem.

    (1990)
  • J.T. Rogers et al.

    J. Biol. Chem.

    (1990)
  • S.S. MacIntyre et al.

    J. Biol. Chem.

    (1985)
  • Y. Itoh et al.

    Biochim. Biophys. Acta

    (1992)
  • A.S. Whitehead et al.

    J. Biol. Chem.

    (1992)
  • D.M. Steel et al.

    Genomics

    (1993)
  • C.A. Lowell et al.

    J. Biol. Chem.

    (1986)
  • G.A. Coetzee et al.

    J. Biol. Chem.

    (1986)
  • R.P. Linke et al.

    Biochem. Biophys. Res. Commun.

    (1991)
  • X. Li et al.

    J. Biol. Chem.

    (1991)
  • M.B. Pepys et al.

    Clin. Rheum. Dis.

    (1982)
  • I. Kushner

    Ann. New York Acad. Sci.

    (1982)
  • C.D. Richards et al.

    J. Immunol.

    (1992)
  • A. Koj et al.

    Biol. Chem. Hoppe-Seyler

    (1993)
  • M.K. Ganapathi

    Biochem. J.

    (1992)
  • D.M. Steel et al.
  • G.H. Fey et al.
  • G. Morrone et al.

    EMBO J.

    (1989)
  • D.M. Steel et al.

    Biochem. J.

    (1993)
  • A. Mackiewicz et al.

    J. Exp. Med.

    (1987)
  • I. Kushner et al.

    Ann. New York Acad. Sci.

    (1982)
  • A. Koj
  • Cited by (889)

    View all citing articles on Scopus
    View full text