ReviewThe use of isolated rat hepatocyte couplets in hepatobiliary physiology
References (39)
- et al.
Tubulovesicular transcytotic transport pathway in isolated rat hepatocyte couplets in culture
Gastroenterology
(1988) The bile salt secretory polarity of hepatocytes
J Hepatol
(1989)- et al.
The transport of bile acids in liver cells
Biochim Biophys Acta
(1988) - et al.
Effect of side chain shortening on the physiological properties of bile acids: hepatic transport and effect of biliary secretion of 23-nor-ursodeoxycholate in rodents
Gastroenterology
(1986) - et al.
Contractility of bile canaliculi: implications for liver function
Science
(1981) - et al.
Isolated rat hepatocyte couplets: a primary secretory unit for electrophysiological studies of bile secretory function
- et al.
Isolated rat hepatocyte couplets in short-term culture — structureral characteristics and plasma membrane reorganization
Hepatology
(1987) - et al.
The epithelial tight junction: structure, function and preliminary biochemical characterization
Mol Cell Biochem
(1988) - et al.
Localization of Na+,K+-ATPase α-subunit to the sinusoidal and lateral but not canalicular membranes of hepatocytes
J Cell Biol
(1987) - et al.
Effects of phalloidin and cytochalasin B on cytoskeletal structures in cultured rat hepatocytes
Cell Tissue Res
(1986)
What is actin doing in the liver cell?
Hepatology
(1983)
Quantitative assessment of canalicular bile formation in isolated hepatocyte couplets using microscopic optical planimetry
J Clin Invest
(1989)
Calcium causes active contraction of bile canaliculi: direct evidence from microinjection studies
Effects of vasopressin and Ca2+ on bile canalicular contraction in isolated hepatocytes
Hepatology
(1986)
Intrahepatic cholestasis as a canalicular motility disorder. Evidence using cytochalasin
Lab Invest
(1983)
The cytoskeleton of the hepatocyte: organization, relationships, and pathology
Osmotic water flux in a two-cell gland derived from isolated hepatocytes
FASEB J
(1989)
Secretion of organic anions in the formation of urine and bile
Pharmacol Rev
(1959)
Canalicular bile salt independent bile formation. Concepts and clues from electrolyte transport in rat liver
Am J Physiol
(1983)
Cited by (49)
Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion
2002, Journal of Biological ChemistryCitation Excerpt :Immunofluorescent staining of isolated hepatocyte couplets and subsequent quantitative analysis further confirmed the subcellular localization of AQP0, AQP8, and AQP9 in hepatocytes as well as demonstrating a d-cAMP-stimulated redistribution of AQP8 (Fig. 4). It has been shown that hepatocyte couplets redevelop their polarity upon isolation and short term culture (23). The interface area between the two coupled cells contains proteins derived from canaliculi, whereas the outer perimeter of the couplets contains proteins derived from basolateral surfaces.
Scavenger receptor BI mediates the selective uptake of oxidized cholesterol esters by rat liver
1999, Journal of Biological ChemistryHepatobiliary effects of tertiary-butylhydroperoxide (tBOOH) in isolated rat hepatocyte couplets
1998, Toxicology and Applied Pharmacology
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