A practical asymmetric synthesis of (R)-fluoxetine and its major metabolite (R)-norfluoxetine☆
A convenient and chromatography-free synthesis for the enantiomers of fluoxetine and norfluoxetine is described.
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This paper is dedicated to Professor Carl R. Johnson on the occasion of his retirement.
Copyright © 2001 Elsevier Science Ltd. All rights reserved.