Original studyParaoxonase gene polymorphism in Japanese subjects with coronary heart disease
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Cited by (121)
Genetic variation at Q192R and L55M polymorphisms in PON1
2016, Environmental Toxicology and PharmacologyParaoxonase 1 gene (Gln<sup>192</sup>-Arg) polymorphism and the risk of coronary artery disease in type 2 diabetes mellitus
2012, Egyptian Heart JournalCitation Excerpt :The molecular basis of this variation and decreased PON1 activity is a polymorphism in the coding region of the gene, resulting in an amino acid substitution glutamine (Gln)/arginine (Arg) in position 192.10,11 Recently, the presence of the (Gln192–Arg) polymorphism in the PON1 gene was reported to be an independent risk factor for CHD in a French Caucasian population and Japanese11 patients with type 2 diabetes and in a North American general population12 but could not be confirmed in Finnish,13 Japanese,14 and Chinese15 CAD patients, mostly without diabetes. To investigate the relationship between PON1 gene polymorphism and the presence, extent and severity of CAD in type 2 DM.
Four genetic polymorphisms of paraoxonase gene and risk of coronary heart disease: A meta-analysis based on 88 case-control studies
2011, AtherosclerosisCitation Excerpt :In the figures, areas of squares of individual studies are inversely proportional to the variances of the log ORs, and the horizontal lines represent confidence intervals (CIs). A total of 88 eligible association studies were identified [6,11–97], with 44 genotyping more than one variant (Supplementary Fig. 1). For the Q192R polymorphism, 76 studies were available, including a total of 22,080 cases and 34,937 controls.
Serum Paraoxonase (PON1) and its Interactions with HDL: Relationship between PON1 and Oxidative Stress
2010, The HDL Handbook: Biological Functions and Clinical ImplicationsThe relationship between paraoxonase1-192 polymorphism and activity with coronary artery disease
2010, Clinical Biochemistry