Expression of the liver Na+-independent organic anion transporting polypeptide (oatp-1) in rats with bile duct ligation
References (27)
- et al.
Stable inducible expression of a functional rat liver organic anion transport protein in Hela cells
J Biol Chem
(1995) - et al.
Ontogenic expression of the Na+-independent organic anion transporting polypeptide (oatp) in rat liver and kidney
J Hepatol
(1996) - et al.
Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver
Gastroenterology
(1995) - et al.
Molecular and functional characterization of bile acid transport in human hepatoblastoma Hep G2 cells
Hepatology
(1996) - et al.
Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization
J Hepatol
(1996) - et al.
Tumor necrosis factor-alpha decreases hepatocytes bile salt uptake and mediates endotoxin-induced cholestasis
Hepatology
(1995) - et al.
Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis
Gastroenterology
(1996) - et al.
Protein measurement with the Folin phenol reagent
J Biol Chem
(1951) - et al.
In situ localization of the hepatocytic Na+/taurocholate-cotransporting polypeptide in rat liver
Gastroenterology
(1994) - et al.
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
Anal Biochem
(1987)
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
J Biol Chem
Dynamics of four rat liver plasma membrane proteins and polymeric IgA receptor
J Biol Chem
Expression of the rat liver Na+/taurocholate cotransporter is regulated in vivo by retention of biliary constituents but not their depletion
Hepatology
Cited by (98)
Mechanisms of Hepatocyte Organic Anion Transport
2018, Physiology of the Gastrointestinal Tract, Sixth EditionMechanisms of Hepatocyte Organic Anion Transport
2012, Physiology of the Gastrointestinal Tract, Two Volume SetMechanisms of Hepatocyte Organic Anion Transport
2012, Physiology of the Gastrointestinal TractRegulation of Hepatobiliary Transporters during Liver Injury
2010, Comprehensive Toxicology, Second EditionPrinciples of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration
2007, Biochimica et Biophysica Acta - Molecular Cell ResearchCitation Excerpt :As an important protective regulatory step, the basolateral Na+-dependent bile acid uptake system, Ntcp, is downregulated to prevent further bile acid uptake by hepatocytes [191–193]. While Oatp1 (Oatp1a1) is also decreased during obstructive cholestasis, maintained Oatp2 (Oatp1a4) and Oatp4 (Oatp1b2) expression ensures continuos elimination of other organic anions into the bile under these conditions and contributes to the progressive nature of obstructive liver damage [192,194,195]. Most prominent is the downregulation of rat Mrp2 to less than 10% of the normal expression after 7 days of CBDL [40].
Liver-homing of purified glucose oxidase: A novel in vivo model of physiological hepatic oxidative stress (H<inf>2</inf>O<inf>2</inf>)
2007, Journal of HepatologyCitation Excerpt :Liver samples were homogenized in PBS on ice in the presence of protease inhibitors (Protease inhibitor cocktail P8340; Sigma, Deisenhofen, Germany) using a glass homogenizer (Wheaton, Millville, NJ). Western blotting was performed using the conditions as described previously [26–32] with the antibody dilutions shown in Table 1. Secondary horseradish peroxidase-conjugated goat anti-rabbit, goat anti-guinea pig, and goat anti-mouse IgG were used at dilutions of 1:3000.