Regular articleTumorigenesis and neoplastic progressionIncreased Expression of P-Glycoprotein and Doxorubicin Chemoresistance of Metastatic Breast Cancer Is Regulated by miR-298
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Supported by grants from the NIH (CA127481 and CA129776) and the Tulane National Primate Research Center (RR000164 to D.K.) and by funds from the Louisiana Cancer Research Consortium (LCRC) and the Tulane University Health Sciences Center (S.D.).
Author contributions: L.B. performed all cellular assays, participated in the design and analysis of the study, and prepared the figures for publication and wrote the manuscript. S.H. participated in analyzing the data and gave valuable suggestions during manuscript writing. S.M. and D.K. performed MicroRNA Array and gave valuable suggestions for the manuscript. K.M. participated in the study design and evaluation. S.D. initiated the studies, participated in the design and coordination of the study, helped analyze and interpret data, and wrote the manuscript.