Topological model for the prediction of MRP1 inhibitory activity of pyrrolopyrimidines and templates derived from pyrrolopyrimidine
Graphical abstract
Wiener’s index—a distance-based topological descriptor has been successfully employed for development of a model for prediction of MRP1 inhibitory activity of pyrrolopyrimidines and their derivatives. Active range of the proposed model possesses vast potential for providing lead structures for development of potent inhibitors of MRP1.
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