Planta Med 2010; 76(17): 2026-2035
DOI: 10.1055/s-0030-1250542
Traditional Chinese Medicine
Reviews
© Georg Thieme Verlag KG Stuttgart · New York

Metabolomics: Towards Understanding Traditional Chinese Medicine

Aihua Zhang1 , Hui Sun1 , Zhigang Wang1 , Wenjun Sun1 , Ping Wang1 , Xijun Wang1
  • 1Heilongjiang University of Chinese Medicine, National TCM Key Lab of Serum Pharmacochemistry, Harbin, China
Further Information

Publication History

received August 1, 2010 revised October 14, 2010

accepted October 21, 2010

Publication Date:
05 November 2010 (online)

Abstract

Metabolomics represent a global understanding of metabolite complement of integrated living systems and dynamic responses to the changes of both endogenous and exogenous factors and has many potential applications and advantages for the research of complex systems. As a systemic approach, metabolomics adopts a “top-down” strategy to reflect the function of organisms from the end products of the metabolic network and to understand metabolic changes of a complete system caused by interventions in a holistic context. This property agrees with the holistic thinking of Traditional Chinese Medicine (TCM), a complex medical science, suggesting that metabolomics has the potential to impact our understanding of the theory behind the evidence-based Chinese medicine. Consequently, the development of robust metabolomic platforms will greatly facilitate, for example, the understanding of the action mechanisms of TCM formulae and the analysis of Chinese herbal (CHM) and mineral medicine, acupuncture, and Chinese medicine syndromes. This review summarizes some of the applications of metabolomics in special TCM issues with an emphasis on metabolic biomarker discovery.

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Prof. PhD. Xijun Wang

National TCM Key Lab of Serum Pharmacochemistry
Heilongjiang University of Chinese Medicine

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Harbin 150040

China

Phone: +86 4 51 82 11 08 18

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Email: phar_research@hotmail.com

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