Original Article
Catechol-O-Methyl Transferase (Comt) in Skin of Patients with Psoriasis*

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Activity of the enzyme COMT in involved areas of skin of patients with psoriasis is much greater than in uninvolved areas of skin of the same patients, or in skill of normal individuals. The relation between activity of the enzyme, high epidermal cell turnover and the distinctive vasodilatation of the capillaries in the dermis is discussed.

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*

From the Department of Medicine, Division of Dermatology, University of Missouri Medical School, Columbia, Missouri 65201.