Gastrointestinal transit of dosage forms in the pig

Davis

,

S. S.

,

Hardy

,

J. G.

,

Fara

,

J. W.

(

1986

)

Transit of pharmaceutical dosage forms through the small intestine

.

Gut

27

:

886

–

892

.

Davis

,

S. S.

,

Hardy

,

J. G.

,

Newman

,

S. P.

,

Wilding

,

I. R.

(

1992

)

Gamma scintigraphy in the evaluation of pharmaceutical dosage forms

.

Eur. J. Nucl. Med.

19

:

971

–

986

.

Devereux

,

J. E.

,

Newton

,

J. M.

,

Short

,

M. B.

(

1990

)

The influence of density on the gastrointestinal transit of pellets

.

J. Pharm. Pharmacol.

42

:

500

–

501

.

Dressman

,

J. B.

,

Yamada

,

K.

(

1991

)

Animal models for oral drug absorption

. In:

Welling

,

P. G.

,

Tse

,

F. L. S.

,

Dighe

,

S. V.

(eds)

Pharmaceutical Bioequivalence

, vol.

48

.

Dekker

,

New York

, pp

727

–

739

.

Google Preview

Fleming

,

S. E.

,

Arce

,

D.

(

1986

)

Using the pigtostudy digestion and fermentation in the gut

. In:

Tumbleson

,

M. E.

(ed.)

Swine in Biomedical Research

.

Plenum Press

,

New York

, p.

124

.

Google Preview

Gardner

,

N.

,

Haresign

,

W.

,

Spiller

,

R.

,

Farraj

,

N.

,

Wiseman

,

J.

,

Norbury

,

H.

,

Illum

,

L.

(

1996

)

Development and validation of a pig model for colon-specific drug delivery

.

J. Pharm. Pharmacol.

48

:

689

–

693

.

Gregory

,

P. C.

,

McFadyen

,

M.

,

Rayner

,

D. V.

(

1990

)

Pattern of gastric emptying in the pig: relation to feeding

.

Br. J. Nutr.

64

:

45

–

58

.

Hildebrand

,

H.

,

McDonald

,

F. M.

,

Windt-Hanke

,

E.

(

1991

)

Characterisation of oral sustained release preparations of iloprost in the pig model by plasma level monitoring

.

Prostaglandins

41

:

473

–

486

.

Hossain

,

M.

,

Abramowitz

,

W.

,

Watrous

,

B. J.

,

Szpunar

,

G. J.

,

Ayres

,

J. W.

(

1990

)

Gastrointestinal transit of nondisintegrating, nonerodible oral dosage forms in pigs

.

Pharm. Res.

7

:

1163

–

1166

.

Johansen

,

H. N.

,

Knudsen

,

Bach K. E.

,

Sandström

,

B.

,

Skjøth

,

F.

(

1996

)

Effects of varying content of soluble dietary fibre from wheat flour and oat milling fractions on gastric emptying in pigs

.

Br. J. Nutr.

75

:

339

–

351

.

Kararli

,

T. T.

(

1995

)

Comparison of the gastrointestinal anatomy, physiology and biochemistry of humans and commonly used laboratory animals

.

Biopharm. Drug Dispos.

16

:

351

–

380

.

Laplace

,

J. P.

,

Tomassone

,

R.

(

1970

)

Evacuation gastro-duodénale chez le porc

.

Ann. Zootech.

19

:

303

–

332

.

Crossref

Larsen

,

F.

,

Jensen

,

Hamborg B.

,

Olesen

,

H. P.

,

Larsen

,

C.

(

1992

)

Multiple oral administration of a ketoprofen-dextran ester prodrug in pigs: assessment of gastrointestinal bioavailability by deconvolution

.

Pharm. Res.

9

:

915

–

919

.

Nimmo

,

W. S.

(

1989

)

Gastric emptying and anaesthesia

.

Can. J. Anaesth.

36

:

S45

–

S47

.

Perkins

,

A. C.

(

1999

) In:

Perkins

,

A. C.

,

Frier

,

M.

(eds)

Instrumentation, imaging, data analysis and display

.

Nuclear Medicine in Pharmaceutical Research

.

Taylor and Francis

,

London

pp

15

–

30

.

Google Preview

Potkins

,

Z. V.

,

Lawrence

,

T. L. J.

,

Thomlinson

,

J. R.

(

1991

)

Effects of structural and non-structural polysaccharides in the diet of the growing pig on gastric emptying rate and rate of passage of digesta to the terminal ileum and through the total gastrointestinal tract

.

Br. J. Nutr.

65

:

391

–

413

.

Rowan

,

A. M.

,

Moughan

,

P. J.

,

Wilson

,

M. N.

,

Maher

,

K.

,

Tasman-Jones

,

C.

(

1994

)

Comparison of the ileal and faecal digestibility of the dietary amino acids in adult humans and evaluation of the pig as a model animal for digestion studies in man

.

Br. J. Nutr.

71

:

29

–

42

.

Ruckebusch

,

Y.

,

Bueno

,

L.

(

1976

)

The effect of feeding on the motility of the stomach and small intestine in the pig

.

Br. J. Nutr.

35

:

397

–

405

.

Treacy

,

P. J.

,

Jamieson

,

G. G.

,

Dent

,

J.

(

1990

)

Pyloric motor function during emptying of a liquid meal from the stomach in the conscious pig

.

J. Physiol.

422

:

523

–

538

.

Weber

,

E.

,

Ehrlein

,

H.-J.

(

1998

)

Relationships between gastric emptying and intestinal absorption of nutrients and energy in mini pigs

.

Digest. Dis. Sci.

43

:

1141

–

1153

.

Crossref

Wilding

,

I. R.

,

Davis

,

S. S.

,

Steed

,

K. P.

,

Sparrow

,

R. A.

,

Westrup

,

J.

,

Hempenstall

,

J. M.

(

1994

)

Gastrointestinal transit of a drug-resinate administered as an oral suspension

.

Int. J. Pharm.

101

:

263

–

268

.

Crossref