ReviewGenetic Polymorphisms of OATP Transporters and Their Impact on Intestinal Absorption and Hepatic Disposition of Drugs
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Cited by (108)
Effect of major components of Tripterygium wilfordii Hook. f on the uptake function of organic anion transporting polypeptide 1B1
2022, Toxicology and Applied PharmacologyDual kinetics of OATP2B1: Inhibitory potency and pH-dependence of OATP2B1 inhibitors
2021, Drug Metabolism and PharmacokineticsMathematical modeling analysis of hepatic uric acid disposition using human sandwich-cultured hepatocytes
2020, Drug Metabolism and PharmacokineticsCitation Excerpt :Although we preliminary observed OATP2B1-mediated transport of uric acid (unpublished observation), at present there is no clear reports about uric acid transport by OATPs. Since OATPs, such as OATP1B1, 1B3 and 2B1, are functional at sinusoidal membrane of hepatocytes [38], further study on OATP-mediated transport of uric acid is required. It is not clear why these transporters may have different contribution to uric acid efflux.
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