The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
EPOXOMICIN, A NEW ANTITUMOR AGENT OF MICROBIAL ORIGIN
MINORU HANADAKOKO SUGAWARAKEIKO KANETASOICHIRO TODAYUJI NISHIYAMAKOJI TOMITAHARUAKI YAMAMOTOMASATAKA KONISHITOSHIKAZU OKI
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1992 Volume 45 Issue 11 Pages 1746-1752

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Abstract

An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of the epoxy-β-aminoketone group, and is closely related to eponemycin.

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© Japan Antibiotics Research Association
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