The role of CYP2B6 in human xenobiotic metabolism

Drug Metab Rev. 1999 Aug;31(3):719-54. doi: 10.1081/dmr-100101942.

Authors

S Ekins¹, S A Wrighton

Affiliation

¹ Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Co., Lilly Corporate Center, Indianapolis, Indiana 46285, USA.

PMID: 10461547
DOI: 10.1081/dmr-100101942

No abstract available

Publication types

Review

MeSH terms

Aryl Hydrocarbon Hydroxylases*
Cytochrome P-450 CYP2B6
Cytochrome P-450 Enzyme System / chemistry
Cytochrome P-450 Enzyme System / genetics
Cytochrome P-450 Enzyme System / immunology
Cytochrome P-450 Enzyme System / metabolism*
Forecasting
Humans
Models, Molecular
Oxidoreductases, N-Demethylating / chemistry
Oxidoreductases, N-Demethylating / genetics
Oxidoreductases, N-Demethylating / immunology
Oxidoreductases, N-Demethylating / metabolism*
Protein Conformation
Substrate Specificity
Xenobiotics / metabolism*

Substances

Xenobiotics
Cytochrome P-450 Enzyme System
Aryl Hydrocarbon Hydroxylases
CYP2B6 protein, human
Cytochrome P-450 CYP2B6
Oxidoreductases, N-Demethylating