The human CYP3A subfamily: practical considerations

Drug Metab Rev. 2000 Aug-Nov;32(3-4):339-61. doi: 10.1081/dmr-100102338.

Authors

S A Wrighton¹, E G Schuetz, K E Thummel, D D Shen, K R Korzekwa, P B Watkins

Affiliation

¹ Department of Drug Disposition, Lilly Corporate Center, Indianapolis, Indiana 46285, USA.

PMID: 11139133
DOI: 10.1081/dmr-100102338

No abstract available

Publication types

Review

MeSH terms

Binding Sites
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System / biosynthesis
Cytochrome P-450 Enzyme System / classification*
Cytochrome P-450 Enzyme System / metabolism
Drug Interactions
Enzyme Induction
Humans
Intestine, Small / enzymology
Kidney / enzymology
Mixed Function Oxygenases / biosynthesis
Mixed Function Oxygenases / classification*
Mixed Function Oxygenases / metabolism
Substrate Specificity

Substances

Cytochrome P-450 Enzyme System
Mixed Function Oxygenases
CYP3A protein, human
Cytochrome P-450 CYP3A