Abstract
Interaction of tea catechins with lipid bilayers has been investigated with liposome systems. Epicatechin gallate had the highest affinity for lipid bilayers, followed by epigallocatechin gallate, epicatechin, and epigallocatechin. Epicatechin gallate and epigallocatechin gallate in the surface of lipid bilayer perturbed the membrane structure.
MeSH terms
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Animals
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology
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Anticarcinogenic Agents / chemistry
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Anticarcinogenic Agents / pharmacology
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Apoptosis / drug effects
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Bacteria / drug effects
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Catechin / chemistry
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Flavonoids*
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Lipid Bilayers / chemistry*
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Models, Molecular
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Molecular Conformation
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Molecular Structure
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Phenols / chemistry*
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Phenols / pharmacology
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Polymers / chemistry*
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Polymers / pharmacology
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Structure-Activity Relationship
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Tea
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Tumor Cells, Cultured
Substances
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Anti-Bacterial Agents
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Anticarcinogenic Agents
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Flavonoids
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Lipid Bilayers
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Phenols
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Polymers
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Tea
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Catechin