Abstract
On the 100th anniversary of Alzheimer's lecture describing the clinicopathological entity which bears his eponym, this article reviews the major areas of progress in our understanding of the disease and outlines the many gaps still remaining. The progress toward effective mechanistic therapy is reviewed.
Publication types
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Historical Article
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Research Support, N.I.H., Intramural
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Review
MeSH terms
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Alzheimer Disease / genetics*
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Alzheimer Disease / history
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Alzheimer Disease / pathology
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Alzheimer Disease / physiopathology*
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Animals
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History, 20th Century
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History, 21st Century
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Humans
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Research / history
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Research Design