Review of P-gp inhibition data in recently approved new drug applications: utility of the proposed [I(1) ]/IC(50) and [I(2) ]/IC(50) criteria in the P-gp decision tree

J Clin Pharmacol. 2013 Feb;53(2):228-33. doi: 10.1177/0091270011436344.
No abstract available

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / antagonists & inhibitors*
  • Decision Trees*
  • Drug Approval
  • Drug Interactions*
  • Drug Labeling
  • Humans
  • Inhibitory Concentration 50

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1