Genetic factors influencing the metabolism of tolbutamide

Pharmacol Ther. 1989;44(2):147-55. doi: 10.1016/0163-7258(89)90064-8.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Cytochrome P-450 Enzyme System / genetics
  • Cytochrome P-450 Enzyme System / metabolism
  • Drug Interactions
  • Humans
  • Hydroxylation
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology
  • Microsomes, Liver / metabolism*
  • Phenotype
  • Tolbutamide / metabolism*
  • Tolbutamide / pharmacokinetics

Substances

  • Cytochrome P-450 Enzyme System
  • Tolbutamide