Abstract
Gastric mucosal damage is a common side effect of nonsteroidal anti-inflammatory drugs (NSAIDs). These drugs may cause gastrointestinal symptoms, gastric erosions, peptic ulcers or upper gastrointestinal bleeding. Therefore, NSAIDs should be used cautiously in patients with a history of gastrointestinal lesions. Drugs that may be useful in preventing or treating NSAID-induced gastric mucosal injury are under intensive clinical investigation.
MeSH terms
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Adult
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Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
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Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
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Aspirin / adverse effects
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Chronic Disease
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Female
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Gastric Mucosa / drug effects*
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Gastric Mucosa / pathology
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Gastrointestinal Hemorrhage / chemically induced
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Gastrointestinal Hemorrhage / diagnosis
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Gastroscopy
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Humans
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Male
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Peptic Ulcer / chemically induced
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Stomach Ulcer / chemically induced
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Stomach Ulcer / diagnosis
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Aspirin