Effects of pregnancy on the metabolism of drugs in the rat and rabbit

Biochem Pharmacol. 1973 Jun 15;22(12):1451-61. doi: 10.1016/0006-2952(73)90323-7.
No abstract available

MeSH terms

  • Animals
  • Cytochrome P-450 Enzyme System / metabolism
  • Female
  • Germ-Free Life
  • Glucuronates / biosynthesis
  • Hexobarbital / pharmacology
  • Hydroxylation
  • Liver / drug effects
  • Liver / enzymology
  • Microsomes, Liver / enzymology
  • Mixed Function Oxygenases / metabolism
  • Nitrate Reductases / metabolism
  • Organ Size
  • Pharmaceutical Preparations / metabolism*
  • Pregnancy
  • Pregnancy, Animal*
  • Rats
  • Sleep / drug effects
  • Time Factors
  • Transferases / metabolism

Substances

  • Glucuronates
  • Pharmaceutical Preparations
  • Cytochrome P-450 Enzyme System
  • Hexobarbital
  • Mixed Function Oxygenases
  • Nitrate Reductases
  • Transferases