Reduction of nitrazepam by Clostridium leptum, a nitroreductase-producing bacterium isolated from the human intestinal tract

Clin Infect Dis. 1997 Sep:25 Suppl 2:S121-2. doi: 10.1086/516204.

Authors

F Rafii¹, J B Sutherland, E B Hansen Jr, C E Cerniglia

Affiliation

¹ Division of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas 72079, USA.

PMID: 9310649
DOI: 10.1086/516204

No abstract available

MeSH terms

Clostridium / metabolism*
Humans
Hydrogen-Ion Concentration
Hypnotics and Sedatives / metabolism*
Intestines / microbiology*
Nitrazepam / metabolism*
Nitroreductases / metabolism*
Oxidation-Reduction

Substances

Hypnotics and Sedatives
Nitrazepam
Nitroreductases