Abstract
The seeds of Calophyllum cerasiferum Vesque (Family-Clusiaceae), and Calophyllum inophyllum Linn. (Family-Clusiaceae) contain several known coumarins, among which were the potent HIV reverse transcriptase inhibitors costatolide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B as its major coumarin constituent in significant amount and thus constitute a renewable source of this compound.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-HIV Agents / chemistry
-
Anti-HIV Agents / isolation & purification*
-
Anti-HIV Agents / pharmacology
-
Coumarins / chemistry
-
Coumarins / isolation & purification*
-
Coumarins / pharmacology
-
Molecular Structure
-
Reverse Transcriptase Inhibitors / chemistry
-
Reverse Transcriptase Inhibitors / isolation & purification*
-
Reverse Transcriptase Inhibitors / pharmacology
Substances
-
Anti-HIV Agents
-
Coumarins
-
Reverse Transcriptase Inhibitors