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Page 1
Clinically Negligible Pharmacokinetic and Pharmacodynamic Interactions Between Lanabecestat and Dabigatran Etexilate, a Prototypical P-gp Substrate.
J Clin Pharmacol. 2020 May;60(5):586-594. doi: 10.1002/jcph.1558. Epub 2019 Dec 18.
J Clin Pharmacol. 2020.
PMID: 31853995
In Vitro and Clinical Evaluations of the Drug-Drug Interaction Potential of a Metabotropic Glutamate 2/3 Receptor Agonist Prodrug with Intestinal Peptide Transporter 1.
Pak YA, Long AJ, Annes WF, Witcher JW, Knadler MP, Ayan-Oshodi MA, Mitchell MI, Leese P, Hillgren KM.
Pak YA, et al. Among authors: ayan oshodi ma.
Drug Metab Dispos. 2017 Feb;45(2):137-144. doi: 10.1124/dmd.116.071118. Epub 2016 Nov 28.
Drug Metab Dispos. 2017.
PMID: 27895114
Free PMC article.
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Disposition and metabolism of semagacestat, a {gamma}-secretase inhibitor, in humans.
Yi P, Hadden C, Kulanthaivel P, Calvert N, Annes W, Brown T, Barbuch RJ, Chaudhary A, Ayan-Oshodi MA, Ring BJ.
Yi P, et al. Among authors: ayan oshodi ma.
Drug Metab Dispos. 2010 Apr;38(4):554-65. doi: 10.1124/dmd.109.030841. Epub 2010 Jan 14.
Drug Metab Dispos. 2010.
PMID: 20075192
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Relative contributions of presystemic and systemic peptidases to oral exposure of a novel metabotropic glutamate 2/3 receptor agonist (LY404039) after oral administration of prodrug pomaglumetad methionil (LY2140023).
Annes WF, Long A, Witcher JW, Ayan-Oshodi MA, Knadler MP, Zhang W, Mitchell MI, Cornelissen K, Hall SD.
Annes WF, et al. Among authors: ayan oshodi ma.
J Pharm Sci. 2015 Jan;104(1):207-14. doi: 10.1002/jps.24226. Epub 2014 Nov 7.
J Pharm Sci. 2015.
PMID: 25382826
Clinical Trial.
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The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole.
Ayan-Oshodi MA, Willis BA, Annes WF, Lowe SL, Friedrich S, de la Peña A, Zhang W, Brown T, Wise SD, Hall SD.
Ayan-Oshodi MA, et al.
Drug Metab Dispos. 2012 Oct;40(10):1945-52. doi: 10.1124/dmd.112.046060. Epub 2012 Jul 12.
Drug Metab Dispos. 2012.
PMID: 22789530
Clinical Trial.
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