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Page 1
FimH Antagonists: Phosphate Prodrugs Improve Oral Bioavailability.
Kleeb S, Jiang X, Frei P, Sigl A, Bezençon J, Bamberger K, Schwardt O, Ernst B. Kleeb S, et al. Among authors: bezencon j. J Med Chem. 2016 Apr 14;59(7):3163-82. doi: 10.1021/acs.jmedchem.5b01923. Epub 2016 Mar 18. J Med Chem. 2016. PMID: 26959338
FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile.
Kleeb S, Pang L, Mayer K, Eris D, Sigl A, Preston RC, Zihlmann P, Sharpe T, Jakob RP, Abgottspon D, Hutter AS, Scharenberg M, Jiang X, Navarra G, Rabbani S, Smiesko M, Lüdin N, Bezençon J, Schwardt O, Maier T, Ernst B. Kleeb S, et al. Among authors: bezencon j. J Med Chem. 2015 Mar 12;58(5):2221-39. doi: 10.1021/jm501524q. Epub 2015 Feb 20. J Med Chem. 2015. PMID: 25666045
FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation.
Klein T, Abgottspon D, Wittwer M, Rabbani S, Herold J, Jiang X, Kleeb S, Lüthi C, Scharenberg M, Bezençon J, Gubler E, Pang L, Smiesko M, Cutting B, Schwardt O, Ernst B. Klein T, et al. Among authors: bezencon j. J Med Chem. 2010 Dec 23;53(24):8627-41. doi: 10.1021/jm101011y. Epub 2010 Nov 24. J Med Chem. 2010. PMID: 21105658
13 results