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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 2
1985 2
1986 1
1988 1
1990 3
1993 1
1997 1
1998 1
1999 1
2002 1
2006 1
2010 1
2011 4
2012 2
2014 1
2015 2
2016 1
2018 3
2019 2
2020 1
2024 0

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28 results

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Page 1
The discovery and optimization of benzimidazoles as selective NaV1.8 blockers for the treatment of pain.
Brown AD, Bagal SK, Blackwell P, Blakemore DC, Brown B, Bungay PJ, Corless M, Crawforth J, Fengas D, Fenwick DR, Gray V, Kemp M, Klute W, Malet Sanz L, Miller D, Murata Y, Payne CE, Skerratt S, Stevens EB, Warmus JS. Brown AD, et al. Among authors: bungay pj. Bioorg Med Chem. 2019 Jan 1;27(1):230-239. doi: 10.1016/j.bmc.2018.12.002. Epub 2018 Dec 4. Bioorg Med Chem. 2019. PMID: 30538065
Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors.
Bagal SK, Omoto K, Blakemore DC, Bungay PJ, Bilsland JG, Clarke PJ, Corbett MS, Cronin CN, Cui JJ, Dias R, Flanagan NJ, Greasley SE, Grimley R, Johnson E, Fengas D, Kitching L, Kraus ML, McAlpine I, Nagata A, Waldron GJ, Warmus JS. Bagal SK, et al. Among authors: bungay pj. J Med Chem. 2019 Jan 10;62(1):247-265. doi: 10.1021/acs.jmedchem.8b00280. Epub 2018 May 3. J Med Chem. 2019. PMID: 29672039
Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin-2 Receptor.
Avgoustou P, Jailani ABA, Zirimwabagabo JO, Tozer MJ, Gibson KR, Glossop PA, Mills JEJ, Porter RA, Blaney P, Bungay PJ, Wang N, Shaw AP, Bigos KJA, Holmes JL, Warrington JI, Skerry TM, Harrity JPA, Richards GO. Avgoustou P, et al. Among authors: bungay pj. ACS Pharmacol Transl Sci. 2020 Jun 25;3(4):706-719. doi: 10.1021/acsptsci.0c00032. eCollection 2020 Aug 14. ACS Pharmacol Transl Sci. 2020. PMID: 32832872 Free PMC article.
Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain.
Bagal SK, Andrews M, Bechle BM, Bian J, Bilsland J, Blakemore DC, Braganza JF, Bungay PJ, Corbett MS, Cronin CN, Cui JJ, Dias R, Flanagan NJ, Greasley SE, Grimley R, James K, Johnson E, Kitching L, Kraus ML, McAlpine I, Nagata A, Ninkovic S, Omoto K, Scales S, Skerratt SE, Sun J, Tran-Dubé M, Waldron GJ, Wang F, Warmus JS. Bagal SK, et al. Among authors: bungay pj. J Med Chem. 2018 Aug 9;61(15):6779-6800. doi: 10.1021/acs.jmedchem.8b00633. Epub 2018 Jul 27. J Med Chem. 2018. PMID: 29944371
Application of PBPK modelling in drug discovery and development at Pfizer.
Jones HM, Dickins M, Youdim K, Gosset JR, Attkins NJ, Hay TL, Gurrell IK, Logan YR, Bungay PJ, Jones BC, Gardner IB. Jones HM, et al. Among authors: bungay pj. Xenobiotica. 2012 Jan;42(1):94-106. doi: 10.3109/00498254.2011.627477. Epub 2011 Oct 30. Xenobiotica. 2012. PMID: 22035569
The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain.
Skerratt SE, Andrews M, Bagal SK, Bilsland J, Brown D, Bungay PJ, Cole S, Gibson KR, Jones R, Morao I, Nedderman A, Omoto K, Robinson C, Ryckmans T, Skinner K, Stupple P, Waldron G. Skerratt SE, et al. Among authors: bungay pj. J Med Chem. 2016 Nov 23;59(22):10084-10099. doi: 10.1021/acs.jmedchem.6b00850. Epub 2016 Nov 4. J Med Chem. 2016. PMID: 27766865
Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain.
Bagal SK, Bungay PJ, Denton SM, Gibson KR, Glossop MS, Hay TL, Kemp MI, Lane CA, Lewis ML, Maw GN, Million WA, Payne CE, Poinsard C, Rawson DJ, Stammen BL, Stevens EB, Thompson LR. Bagal SK, et al. Among authors: bungay pj. ACS Med Chem Lett. 2015 Apr 29;6(6):650-4. doi: 10.1021/acsmedchemlett.5b00059. eCollection 2015 Jun 11. ACS Med Chem Lett. 2015. PMID: 26101568 Free PMC article.
28 results