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The Dolaflexin-based Antibody-Drug Conjugate XMT-1536 Targets the Solid Tumor Lineage Antigen SLC34A2/NaPi2b.
Bodyak ND, Mosher R, Yurkovetskiy AV, Yin M, Bu C, Conlon PR, Demady DR, DeVit MJ, Gumerov DR, Gurijala VR, Lee W, McGillicuddy D, Park PU, Poling LL, Protopova M, Qin L, Stevenson CA, Ter-Ovanesyan E, Uttard A, Xiao D, Xu J, Xu L, Bergstrom DA, Lowinger TB. Bodyak ND, et al. Among authors: demady dr. Mol Cancer Ther. 2021 May;20(5):896-905. doi: 10.1158/1535-7163.MCT-20-0183. Epub 2021 Mar 15. Mol Cancer Ther. 2021. PMID: 33722858
Discovery of novel polyamide-pyrrolobenzodiazepine hybrids for antibody-drug conjugates.
Thomas JD, Yurkovetskiy AV, Yin M, Bodyak ND, Gumerov DR, Tang S, Kelleher E, Jones BD, Protopopova M, Qin L, Uttard A, Demady DR, Lowinger TB. Thomas JD, et al. Among authors: demady dr. Bioorg Med Chem Lett. 2022 Sep 15;72:128876. doi: 10.1016/j.bmcl.2022.128876. Epub 2022 Jul 3. Bioorg Med Chem Lett. 2022. PMID: 35788036
Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates.
Thomas JD, Yurkovetskiy AV, Yin M, Bodyak ND, Tang S, Protopopova M, Kelleher E, Jones B, Yang L, Custar D, Catcott KC, Demady DR, Collins SD, Xu L, Bu C, Qin L, Ter-Ovanesyan E, Damelin M, Toader D, Lowinger TB. Thomas JD, et al. Among authors: demady dr. Mol Cancer Ther. 2024 Feb 14. doi: 10.1158/1535-7163.MCT-23-0622. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38354416
Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.
Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Mariggio MA, Onofrj M, Thomas A, Li H, Mangold JE, Signore AP, Demarco U, Demady DR, Nabili P, Lazrove E, Smith PJ, Gribkoff VK, Jonas EA. Alavian KN, et al. Among authors: demady dr. Brain Res. 2012 Mar 29;1446:1-11. doi: 10.1016/j.brainres.2012.01.046. Epub 2012 Jan 28. Brain Res. 2012. PMID: 22364637 Free PMC article.
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