Denissen JF[au] - Search Results

Year	Number of Results
1994	1
1995	1
1996	3
1997	2
1998	2
1999	1
2004	1
2024	0

1

ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.

Kempf DJ, Marsh KC, Denissen JF, McDonald E, Vasavanonda S, Flentge CA, Green BE, Fino L, Park CH, Kong XP, et al. Kempf DJ, et al. Among authors: denissen jf. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2484-8. doi: 10.1073/pnas.92.7.2484. Proc Natl Acad Sci U S A. 1995. PMID: 7708670 Free PMC article.

2

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

Kempf DJ, Marsh KC, Kumar G, Rodrigues AD, Denissen JF, McDonald E, Kukulka MJ, Hsu A, Granneman GR, Baroldi PA, Sun E, Pizzuti D, Plattner JJ, Norbeck DW, Leonard JM. Kempf DJ, et al. Among authors: denissen jf. Antimicrob Agents Chemother. 1997 Mar;41(3):654-60. doi: 10.1128/AAC.41.3.654. Antimicrob Agents Chemother. 1997. PMID: 9056009 Free PMC article.

3

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

Kumar GN, Rodrigues AD, Buko AM, Denissen JF. Kumar GN, et al. Among authors: denissen jf. J Pharmacol Exp Ther. 1996 Apr;277(1):423-31. J Pharmacol Exp Ther. 1996. PMID: 8613951

4

Human serum attenuates the activity of protease inhibitors toward wild-type and mutant human immunodeficiency virus.

Molla A, Vasavanonda S, Kumar G, Sham HL, Johnson M, Grabowski B, Denissen JF, Kohlbrenner W, Plattner JJ, Leonard JM, Norbeck DW, Kempf DJ. Molla A, et al. Among authors: denissen jf. Virology. 1998 Oct 25;250(2):255-62. doi: 10.1006/viro.1998.9383. Virology. 1998. PMID: 9792836 Free article.

5

Metabolism and disposition of the HIV-1 protease inhibitor ritonavir (ABT-538) in rats, dogs, and humans.

Denissen JF, Grabowski BA, Johnson MK, Buko AM, Kempf DJ, Thomas SB, Surber BW. Denissen JF, et al. Drug Metab Dispos. 1997 Apr;25(4):489-501. Drug Metab Dispos. 1997. PMID: 9107549

6

Metabolism and disposition of the HIV-1 protease inhibitor lopinavir (ABT-378) given in combination with ritonavir in rats, dogs, and humans.

Kumar GN, Jayanti VK, Johnson MK, Uchic J, Thomas S, Lee RD, Grabowski BA, Sham HL, Kempf DJ, Denissen JF, Marsh KC, Sun E, Roberts SA. Kumar GN, et al. Among authors: denissen jf. Pharm Res. 2004 Sep;21(9):1622-30. doi: 10.1023/b:pham.0000041457.64638.8d. Pharm Res. 2004. PMID: 15497688

7

A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.

Sham HL, Zhao C, Stewart KD, Betebenner DA, Lin S, Park CH, Kong XP, Rosenbrook W Jr, Herrin T, Madigan D, Vasavanonda S, Lyons N, Molla A, Saldivar A, Marsh KC, McDonald E, Wideburg NE, Denissen JF, Robins T, Kempf DJ, Plattner JJ, Norbeck DW. Sham HL, et al. Among authors: denissen jf. J Med Chem. 1996 Jan 19;39(2):392-7. doi: 10.1021/jm9507183. J Med Chem. 1996. PMID: 8558507

8

Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists.

Curtin ML, Davidsen SK, Heyman HR, Garland RB, Sheppard GS, Florjancic AS, Xu L, Carrera GM Jr, Steinman DH, Trautmann JA, Albert DH, Magoc TJ, Tapang P, Rhein DA, Conway RG, Luo G, Denissen JF, Marsh KC, Morgan DW, Summers JB. Curtin ML, et al. Among authors: denissen jf. J Med Chem. 1998 Jan 1;41(1):74-95. doi: 10.1021/jm970389+. J Med Chem. 1998. PMID: 9438024

9

In vitro metabolism of the HIV-1 protease inhibitor ABT-378: species comparison and metabolite identification.

Kumar GN, Jayanti V, Lee RD, Whittern DN, Uchic J, Thomas S, Johnson P, Grabowski B, Sham H, Betebenner D, Kempf DJ, Denissen JF. Kumar GN, et al. Among authors: denissen jf. Drug Metab Dispos. 1999 Jan;27(1):86-91. Drug Metab Dispos. 1999. PMID: 9884314

10

Hepatic drug-metabolizing activities in rats after 14 days of oral administration of the human immunodeficiency virus-type 1 protease inhibitor ritonavir (ABT-538).

Kumar GN, Grabowski B, Lee R, Denissen JF. Kumar GN, et al. Among authors: denissen jf. Drug Metab Dispos. 1996 May;24(5):615-7. Drug Metab Dispos. 1996. PMID: 8723745 No abstract available.

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