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Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.
Curreli F, Belov DS, Kwon YD, Ramesh R, Furimsky AM, O'Loughlin K, Byrge PC, Iyer LV, Mirsalis JC, Kurkin AV, Altieri A, Debnath AK. Curreli F, et al. Among authors: furimsky am. Eur J Med Chem. 2018 Jun 25;154:367-391. doi: 10.1016/j.ejmech.2018.04.062. Epub 2018 May 12. Eur J Med Chem. 2018. PMID: 29860061 Free PMC article.
Pharmacokinetics and metabolism of (R,R)-methoxyfenoterol in rat.
Siluk D, Mager DE, Kim HS, Wang Y, Furimsky AM, Ta A, Iyer LV, Green CE, Wainer IW. Siluk D, et al. Among authors: furimsky am. Xenobiotica. 2010 Mar;40(3):195-206. doi: 10.3109/00498250903434533. Xenobiotica. 2010. PMID: 20039779 Free PMC article.