Halladay JS[au] - Search Results

Year	Number of Results
1999	1
2002	1
2007	1
2009	3
2010	1
2011	7
2012	4
2013	2
2014	1
2015	1
2016	1
2017	3
2021	1
2022	1
2024	0

1

Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity.

Khojasteh SC, Prabhu S, Kenny JR, Halladay JS, Lu AY. Khojasteh SC, et al. Among authors: halladay js. Eur J Drug Metab Pharmacokinet. 2011 Mar;36(1):1-16. doi: 10.1007/s13318-011-0024-2. Epub 2011 Feb 19. Eur J Drug Metab Pharmacokinet. 2011. PMID: 21336516 Review.

2

Going Beyond Common Drug Metabolizing Enzymes: Case Studies of Biotransformation Involving Aldehyde Oxidase, γ-Glutamyl Transpeptidase, Cathepsin B, Flavin-Containing Monooxygenase, and ADP-Ribosyltransferase.

Fan PW, Zhang D, Halladay JS, Driscoll JP, Khojasteh SC. Fan PW, et al. Among authors: halladay js. Drug Metab Dispos. 2016 Aug;44(8):1253-61. doi: 10.1124/dmd.116.070169. Epub 2016 Apr 26. Drug Metab Dispos. 2016. PMID: 27117704 Review.

3

Discovery of an orally active benzoxaborole prodrug effective in the treatment of Chagas disease in non-human primates.

Padilla AM, Wang W, Akama T, Carter DS, Easom E, Freund Y, Halladay JS, Liu Y, Hamer SA, Hodo CL, Wilkerson GK, Orr D, White B, George A, Shen H, Jin Y, Wang MZ, Tse S, Jacobs RT, Tarleton RL. Padilla AM, et al. Among authors: halladay js. Nat Microbiol. 2022 Oct;7(10):1536-1546. doi: 10.1038/s41564-022-01211-y. Epub 2022 Sep 5. Nat Microbiol. 2022. PMID: 36065062 Free PMC article.

4

Novel Mechanism of Decyanation of GDC-0425 by Cytochrome P450.

Takahashi RH, Halladay JS, Siu M, Chen Y, Hop CE, Khojasteh SC, Ma S. Takahashi RH, et al. Among authors: halladay js. Drug Metab Dispos. 2017 May;45(5):430-440. doi: 10.1124/dmd.116.074336. Epub 2017 Feb 10. Drug Metab Dispos. 2017. PMID: 28188299

5

Case Study 9: Probe-Dependent Binding Explains Lack of CYP2C9 Inactivation by 1-Aminobenzotriazole (ABT).

Sodhi JK, Halladay JS. Sodhi JK, et al. Among authors: halladay js. Methods Mol Biol. 2021;2342:765-779. doi: 10.1007/978-1-0716-1554-6_28. Methods Mol Biol. 2021. PMID: 34272716

6

1-Aminobenzotriazole coincubated with (S)-warfarin results in potent inactivation of CYP2C9.

Sodhi JK, Ford KA, Mukadam S, Wong S, Hop CE, Khojasteh SC, Halladay JS. Sodhi JK, et al. Among authors: halladay js. Drug Metab Dispos. 2014 May;42(5):813-7. doi: 10.1124/dmd.113.055913. Epub 2014 Feb 18. Drug Metab Dispos. 2014. PMID: 24550229

7

A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.

Sodhi JK, Wong S, Kirkpatrick DS, Liu L, Khojasteh SC, Hop CE, Barr JT, Jones JP, Halladay JS. Sodhi JK, et al. Among authors: halladay js. Drug Metab Dispos. 2015 Jun;43(6):908-15. doi: 10.1124/dmd.114.061804. Epub 2015 Apr 6. Drug Metab Dispos. 2015. PMID: 25845827 Free PMC article.

8

The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters.

Cheong J, Halladay JS, Plise E, Sodhi JK, Salphati L. Cheong J, et al. Among authors: halladay js. Drug Metab Lett. 2017;11(2):111-118. doi: 10.2174/1872312811666171010101248. Drug Metab Lett. 2017. PMID: 29032766

9

Metabolism and disposition of [(14)C]1-nitronaphthalene in male Sprague-Dawley rats.

Halladay JS, Sauer JM, Sipes IG. Halladay JS, et al. Drug Metab Dispos. 1999 Dec;27(12):1456-65. Drug Metab Dispos. 1999. PMID: 10570027

10

Formation of a quinoneimine intermediate of 4-fluoro-N-methylaniline by FMO1: carbon oxidation plus defluorination.

Driscoll JP, Aliagas I, Harris JJ, Halladay JS, Khatib-Shahidi S, Deese A, Segraves N, Khojasteh-Bakht SC. Driscoll JP, et al. Among authors: halladay js. Chem Res Toxicol. 2010 May 17;23(5):861-3. doi: 10.1021/tx1000688. Chem Res Toxicol. 2010. PMID: 20369854

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