Heikkinen AT[au] - Search Results

Year	Number of Results
2007	2
2008	4
2009	5
2010	3
2012	2
2013	2
2014	2
2015	5
2016	2
2017	1
2019	3
2020	2
2021	1
2023	1
2024	0

1

PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5'-Diphospho-glucuronosyltransferase Substrates.

Reddy MB, Bolger MB, Fraczkiewicz G, Del Frari L, Luo L, Lukacova V, Mitra A, Macwan JS, Mullin JM, Parrott N, Heikkinen AT. Reddy MB, et al. Among authors: heikkinen at. Pharmaceutics. 2021 Aug 24;13(9):1325. doi: 10.3390/pharmaceutics13091325. Pharmaceutics. 2021. PMID: 34575401 Free PMC article. Review.

2

Analysis of the Bile Acid Composition in a Fibroblast Growth Factor 19-Expressing Liver-Humanized Mouse Model and Its Use for CYP3A4-Mediated Drug-Drug Interaction Studies.

Mezler M, Jones RS, Sangaraju D, Goldman DC, Hoffmann M, Heikkinen AT, Mannila J, Chang JH, Foquet L, Pusalkar S, Chothe PP, Scheer N. Mezler M, et al. Among authors: heikkinen at. Drug Metab Dispos. 2023 Oct;51(10):1391-1402. doi: 10.1124/dmd.123.001398. Epub 2023 Jul 31. Drug Metab Dispos. 2023. PMID: 37524541

3

Analysis of unstirred water layer in in vitro permeability experiments.

Korjamo T, Heikkinen AT, Mönkkönen J. Korjamo T, et al. Among authors: heikkinen at. J Pharm Sci. 2009 Dec;98(12):4469-79. doi: 10.1002/jps.21762. J Pharm Sci. 2009. PMID: 19653267 Review.

4

Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case Studies.

Miller NA, Reddy MB, Heikkinen AT, Lukacova V, Parrott N. Miller NA, et al. Among authors: heikkinen at. Clin Pharmacokinet. 2019 Jun;58(6):727-746. doi: 10.1007/s40262-019-00741-9. Clin Pharmacokinet. 2019. PMID: 30729397 Review.

5

Modelling of drug disposition kinetics in in vitro intestinal absorption cell models.

Heikkinen AT, Korjamo T, Mönkkönen J. Heikkinen AT, et al. Basic Clin Pharmacol Toxicol. 2010 Mar;106(3):180-8. doi: 10.1111/j.1742-7843.2009.00504.x. Epub 2009 Dec 22. Basic Clin Pharmacol Toxicol. 2010. PMID: 20030630 Free article. Review.

6

Physiologically based pharmacokinetic modelling of oxycodone drug-drug interactions.

Rytkönen J, Ranta VP, Kokki M, Kokki H, Hautajärvi H, Rinne V, Heikkinen AT. Rytkönen J, et al. Among authors: heikkinen at. Biopharm Drug Dispos. 2020 Feb;41(1-2):72-88. doi: 10.1002/bdd.2215. Biopharm Drug Dispos. 2020. PMID: 31925778

7

In vitro methods to study the interplay of drug metabolism and efflux in the intestine.

Siissalo S, Heikkinen AT. Siissalo S, et al. Among authors: heikkinen at. Curr Drug Metab. 2013 Jan;14(1):102-11. Curr Drug Metab. 2013. PMID: 22497570 Review.

8

Metabolism of Scoparone in Experimental Animals and Humans.

Juvonen RO, Novák F, Emmanouilidou E, Auriola S, Timonen J, Heikkinen AT, Küblbeck J, Finel M, Raunio H. Juvonen RO, et al. Among authors: heikkinen at. Planta Med. 2019 Apr;85(6):453-464. doi: 10.1055/a-0835-2301. Epub 2019 Feb 8. Planta Med. 2019. PMID: 30736072

9

The role of quantitative ADME proteomics to support construction of physiologically based pharmacokinetic models for use in small molecule drug development.

Heikkinen AT, Lignet F, Cutler P, Parrott N. Heikkinen AT, et al. Proteomics Clin Appl. 2015 Aug;9(7-8):732-44. doi: 10.1002/prca.201400147. Epub 2015 Apr 13. Proteomics Clin Appl. 2015. PMID: 25676057 Review.

10

In vitro-in vivo correlation in P-glycoprotein mediated transport in intestinal absorption.

del Amo EM, Heikkinen AT, Mönkkönen J. del Amo EM, et al. Among authors: heikkinen at. Eur J Pharm Sci. 2009 Feb 15;36(2-3):200-11. doi: 10.1016/j.ejps.2008.11.005. Epub 2008 Nov 19. Eur J Pharm Sci. 2009. PMID: 19063964 Review.

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