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Urotensin II acts as a modulator of mesopontine cholinergic neurons.
Clark SD, Nothacker HP, Blaha CD, Tyler CJ, Duangdao DM, Grupke SL, Helton DR, Leonard CS, Civelli O. Clark SD, et al. Among authors: helton dr. Brain Res. 2005 Oct 19;1059(2):139-48. doi: 10.1016/j.brainres.2005.08.026. Epub 2005 Sep 23. Brain Res. 2005. PMID: 16183039
Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties.
Monn JA, Valli MJ, Massey SM, Wright RA, Salhoff CR, Johnson BG, Howe T, Alt CA, Rhodes GA, Robey RL, Griffey KR, Tizzano JP, Kallman MJ, Helton DR, Schoepp DD. Monn JA, et al. Among authors: helton dr. J Med Chem. 1997 Feb 14;40(4):528-37. doi: 10.1021/jm9606756. J Med Chem. 1997. PMID: 9046344
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