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Biodistribution of Lipid 5, mRNA, and Its Translated Protein Following Intravenous Administration of mRNA-Encapsulated Lipid Nanoparticles in Rats.
Ci L, Hard M, Zhang H, Gandham S, Hua S, Wickwire J, Wehrman T, Slauter R, Auerbach A, Kenney M, Mercer G, Hendrick T, Almarsson Ö, Cheung E, Burdette D. Ci L, et al. Among authors: hendrick t. Drug Metab Dispos. 2023 Jul;51(7):813-823. doi: 10.1124/dmd.122.000980. Epub 2023 May 19. Drug Metab Dispos. 2023. PMID: 37208184
Systemic Exposure, Metabolism, and Elimination of [14C]-Labeled Amino Lipid, Lipid 5, after a Single Administration of mRNA Encapsulating Lipid Nanoparticles to Sprague-Dawley Rats.
Burdette D, Ci L, Shilliday B, Slauter R, Auerbach A, Kenney M, Almarsson Ö, Cheung E, Hendrick T. Burdette D, et al. Among authors: hendrick t. Drug Metab Dispos. 2023 Jul;51(7):804-812. doi: 10.1124/dmd.122.001194. Epub 2023 May 19. Drug Metab Dispos. 2023. PMID: 37208185