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Year Number of Results
2013 1
2014 1
2015 2
2016 2
2017 1
2018 2
2019 1
2020 2
2021 2
2024 0

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Page 1
Preclinical Comparison of the Blood-brain barrier Permeability of Osimertinib with Other EGFR TKIs.
Colclough N, Chen K, Johnström P, Strittmatter N, Yan Y, Wrigley GL, Schou M, Goodwin R, Varnäs K, Adua SJ, Zhao M, Nguyen DX, Maglennon G, Barton P, Atkinson J, Zhang L, Janefeldt A, Wilson J, Smith A, Takano A, Arakawa R, Kondrashov M, Malmquist J, Revunov E, Vazquez-Romero A, Moein MM, Windhorst AD, Karp NA, Finlay MRV, Ward RA, Yates JWT, Smith PD, Farde L, Cheng Z, Cross DAE. Colclough N, et al. Among authors: janefeldt a. Clin Cancer Res. 2021 Jan 1;27(1):189-201. doi: 10.1158/1078-0432.CCR-19-1871. Epub 2020 Oct 7. Clin Cancer Res. 2021. PMID: 33028591
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.
Durant ST, Zheng L, Wang Y, Chen K, Zhang L, Zhang T, Yang Z, Riches L, Trinidad AG, Fok JHL, Hunt T, Pike KG, Wilson J, Smith A, Colclough N, Reddy VP, Sykes A, Janefeldt A, Johnström P, Varnäs K, Takano A, Ling S, Orme J, Stott J, Roberts C, Barrett I, Jones G, Roudier M, Pierce A, Allen J, Kahn J, Sule A, Karlin J, Cronin A, Chapman M, Valerie K, Illingworth R, Pass M. Durant ST, et al. Among authors: janefeldt a. Sci Adv. 2018 Jun 20;4(6):eaat1719. doi: 10.1126/sciadv.aat1719. eCollection 2018 Jun. Sci Adv. 2018. PMID: 29938225 Free PMC article.
Primary Human Hepatocyte Spheroid Model as a 3D In Vitro Platform for Metabolism Studies.
Kanebratt KP, Janefeldt A, Vilén L, Vildhede A, Samuelsson K, Milton L, Björkbom A, Persson M, Leandersson C, Andersson TB, Hilgendorf C. Kanebratt KP, et al. Among authors: janefeldt a. J Pharm Sci. 2021 Jan;110(1):422-431. doi: 10.1016/j.xphs.2020.10.043. Epub 2020 Oct 26. J Pharm Sci. 2021. PMID: 33122050 Free article.
Structural and functional characterization of a specific antidote for ticagrelor.
Buchanan A, Newton P, Pehrsson S, Inghardt T, Antonsson T, Svensson P, Sjögren T, Öster L, Janefeldt A, Sandinge AS, Keyes F, Austin M, Spooner J, Gennemark P, Penney M, Howells G, Vaughan T, Nylander S. Buchanan A, et al. Among authors: janefeldt a. Blood. 2015 May 28;125(22):3484-90. doi: 10.1182/blood-2015-01-622928. Epub 2015 Mar 18. Blood. 2015. PMID: 25788700 Free PMC article.
The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids.
Prill S, Caddeo A, Baselli G, Jamialahmadi O, Dongiovanni P, Rametta R, Kanebratt KP, Pujia A, Pingitore P, Mancina RM, Lindén D, Whatling C, Janefeldt A, Kozyra M, Ingelman-Sundberg M, Valenti L, Andersson TB, Romeo S. Prill S, et al. Among authors: janefeldt a. Sci Rep. 2019 Aug 12;9(1):11585. doi: 10.1038/s41598-019-47737-w. Sci Rep. 2019. PMID: 31406127 Free PMC article.
Unraveling the pharmacokinetic interaction of ticagrelor and MEDI2452 (Ticagrelor antidote) by mathematical modeling.
Almquist J, Penney M, Pehrsson S, Sandinge AS, Janefeldt A, Maqbool S, Madalli S, Goodman J, Nylander S, Gennemark P. Almquist J, et al. Among authors: janefeldt a. CPT Pharmacometrics Syst Pharmacol. 2016 Jun;5(6):313-23. doi: 10.1002/psp4.12089. Epub 2016 Jun 16. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27310493 Free PMC article.
11 results