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Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation.
Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3708-3711. doi: 10.1016/j.bmcl.2018.10.023. Epub 2018 Oct 15.
Bioorg Med Chem Lett. 2018.
PMID: 30389287
Novel Bioactivation Pathway of Benzbromarone Mediated by Cytochrome P450.
Kitagawara Y, Ohe T, Tachibana K, Takahashi K, Nakamura S, Mashino T.
Kitagawara Y, et al.
Drug Metab Dispos. 2015 Sep;43(9):1303-6. doi: 10.1124/dmd.115.065037. Epub 2015 Jun 23.
Drug Metab Dispos. 2015.
PMID: 26106235
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Ipso substitution of bisphenol A catalyzed by microsomal cytochrome P450 and enhancement of estrogenic activity.
Nakamura S, Tezuka Y, Ushiyama A, Kawashima C, Kitagawara Y, Takahashi K, Ohta S, Mashino T.
Nakamura S, et al. Among authors: kitagawara y.
Toxicol Lett. 2011 May 30;203(1):92-5. doi: 10.1016/j.toxlet.2011.03.010. Epub 2011 Mar 23.
Toxicol Lett. 2011.
PMID: 21402134
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